All formulas, either concentrates or ready-to-feed, have some fluoride, but most infant formula manufacturers develop their products to ensure low levels of fluoride.

A study by the ADA confirmed that fluoride concentrations in commercially available infant formulas are very low.

It is not possible to remove this small amount of fluoride by filtering or boiling the formula; however, at normal consumption amounts, infant formula alone does not contain fluoride at levels that would be higher than the daily upper limit established by the Institute of Medicine. In liquid or powdered infant formula concentrate, the majority of fluoride comes from the water used to mix the formula. Some parents may choose to use bottled water.